Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

The discovery and development of a biological active molecule with therapeutic properties is an ever increasing complex task, highly unpredictable at the early stages and marked, in the end, by high rates of failure. As a consequence, the overall process leading to the production of a successful drug is very costly. The improvement of the net outcome in drug discovery and development would require, amongst other important factors, a good understanding of the molecular events that characterize the disease or pathology in order to better identify likely targets of interest, to optimize the interaction of an active agent (small molecule or macromolecule of natural or synthetic origin) with those targets, and to facilitate the study of the pharmacokinetics, pharmacodynamics and toxicity of an active agent in suitable models and in human subjects. The objective of this Research Topic is to highlight new developments and applications of imaging techniques with the objective of performing pharmacological studies in vivo, in animal models and in humans. In the domain of drug discovery, the pharmacological and biomedical questions constitute the center of attention. In this sense, it is fundamental to keep in mind the strengths and limitations of each analytical or imaging technique. At the end, the judicious application of the technique with the aim of supporting the search for answers to manifold questions arising during a long and painstaking path provides a continuous role for imaging within the complex area of drug discovery and development.

magnetic resonance imaging (MRI) --- computerized tomography(CT) --- positron emission tomography (PET) --- pharmacology --- single photon emission computed tomography (SPECT) --- imaging --- medical imaging --- ultrasound

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

The discovery and development of a biological active molecule with therapeutic properties is an ever increasing complex task, highly unpredictable at the early stages and marked, in the end, by high rates of failure. As a consequence, the overall process leading to the production of a successful drug is very costly. The improvement of the net outcome in drug discovery and development would require, amongst other important factors, a good understanding of the molecular events that characterize the disease or pathology in order to better identify likely targets of interest, to optimize the interaction of an active agent (small molecule or macromolecule of natural or synthetic origin) with those targets, and to facilitate the study of the pharmacokinetics, pharmacodynamics and toxicity of an active agent in suitable models and in human subjects. The objective of this Research Topic is to highlight new developments and applications of imaging techniques with the objective of performing pharmacological studies in vivo, in animal models and in humans. In the domain of drug discovery, the pharmacological and biomedical questions constitute the center of attention. In this sense, it is fundamental to keep in mind the strengths and limitations of each analytical or imaging technique. At the end, the judicious application of the technique with the aim of supporting the search for answers to manifold questions arising during a long and painstaking path provides a continuous role for imaging within the complex area of drug discovery and development.

magnetic resonance imaging (MRI) --- computerized tomography(CT) --- positron emission tomography (PET) --- pharmacology --- single photon emission computed tomography (SPECT) --- imaging --- medical imaging --- ultrasound

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Since its introduction in 1972, X-ray computed tomography (CT) has evolved into an essential diagnostic imaging tool for a continually increasing variety of clinical applications. The goal of this book was not simply to summarize currently available CT imaging techniques but also to provide clinical perspectives, advances in hybrid technologies, new applications other than medicine and an outlook on future developments. Major experts in this growing field contributed to this book, which is geared to radiologists, orthopedic surgeons, engineers, and clinical and basic researchers. We believe that CT scanning is an effective and essential tools in treatment planning, basic understanding of physiology, and and tackling the ever-increasing challenge of diagnosis in our society.

Tomography --- Industrial applications. --- Body section radiography --- Computed tomography --- Computer tomography --- Computerized tomography --- CT (Computed tomography) --- Laminagraphy --- Laminography --- Radiological stratigraphy --- Stratigraphy, Radiological --- Tomographic imaging --- Zonography --- Cross-sectional imaging --- Radiography, Medical --- Geometric tomography --- Radiology

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This book is a research publication that covers developments within the Diagnostics field of study. The book is a collection of reviewed scholarly contributions written by different authors and edited by an expert with specific expertise. Each scholarly contribution represents a chapter which is complete in itself but related to the major topics and objectives. The target audience comprises scholars and specialists in the field.

Tomography. --- Body section radiography --- Computed tomography --- Computer tomography --- Computerized tomography --- CT (Computed tomography) --- Laminagraphy --- Laminography --- Radiological stratigraphy --- Stratigraphy, Radiological --- Tomographic imaging --- Zonography --- Cross-sectional imaging --- Radiography, Medical --- Geometric tomography --- Radiology

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This book offers a comprehensive and topical depiction of advances in CT imaging. CT has become a leading medical imaging modality, thanks to its superb spatial and temporal resolution to depict anatomical details. New advances have further extended the technology to provide physiological information, enabling a wide and expanding range of clinical applications. The text covers the latest advancements in CT technology and clinical applications for a variety of CT types and imaging methods. The content is presented in seven parts to offer a structure across a board coverage of CT: CT Systems, CT Performance, CT Practice, Spectral CT, Quantitative CT, Functional CT, and Special Purpose CT. Each contain chapters written by leading experts in the field, covering CT hardware and software innovations, CT operation, CT performance characterization, functional and quantitative applications, and CT systems devised for specific anatomical applications. This book is an ideal resource for practitioners of CT applications in medicine, including physicians, trainees, engineers, and scientists. .

Radiology. --- Imaging / Radiology. --- Tomography. --- Body section radiography --- Computed tomography --- Computerized tomography --- CT (Computer tomography) --- Laminagraphy --- Laminography --- Radiological stratigraphy --- Stratigraphy, Radiological --- Tomographic imaging --- Zonography --- Cross-sectional imaging --- Radiography, Medical --- Geometric tomography --- Computer tomography --- CT (Computed tomography) --- Radiological physics --- Physics --- Radiation